Please disable your Ad Blocker to better interact with this website.

A wide-ranging new study on the effects of puberty blockers used on transgender children shows that instead helping them, the drugs wreck serious and permanent damage to their bodies and minds.

Using powerful drugs to stop children from reaching puberty has been a major tool for transgenderism for 25 years at this point and forms an integral part of sex changes on children. Since the mid 1990s, this drug protocol — called the “Dutch Protocol” — has been uncritically presented as the best way to treat children who exhibit so-called “gender dysphoria,” the feeling that they should have been born as the opposite gender.

But after 25 years, this new study finds that the drugs have serious and dangerous side effects and end up doing far more harm than good when these patients reach their adulthood.

The new study, published on September 19 in the Journal of Sex and Marital Therapy, entitled The Dutch Protocol for Juvenile Transsexuals: Origins and Evidence, set out to “review the history of this intervention and scrutinizes the evidence adduced to support it,” and finds that the evidence is conclusive that puberty suppression has “deleterious physical effects.”

The article, authored by Oxford University’s Dr. Michael Biggs, says that these widely used drugs, known as luteinizing hormone-releasing hormone agonists or GnRHa drugs, are creating sexless adults, are depleting victims’ bone density, hampering their cognitive development, and producing a myriad of deleterious emotional effects later in life.

The puberty blocking drug protocols were initially proposed by Dutch clinicians at Utrecht and Amsterdam and were touted as safe, easy, and even reversible. One reason for the initial proposal was for use as punishment for male sex criminals to chemically castrate them and take away their desire for sex. But the protocol was also proposed as therapy for pre-teen and teenaged “transsexuals.”

Recounting the origins of the therapy, Biggs noted that boys were given anti-androgen and cyproterone acetate, to prevent erections and causing breasts to grow. The next step was to have their male genitals surgically removed. And conversely, Girls were given progestin to stop menstruation along with testosterone to promote hair growth, etc. They were also subjected to permanent double mastectomies, hysterectomies, and oophorectomies.

Aside from loss of bone density, another serious side effect is that these children are never able to experience an orgasm, no matter what gender they think they’ve transformed into. These drugs turn them into people who can never experience any sexual pleasure whatsoever. And that is a state that cannot ever be reversed.

The protocols, created by Dutch doctor Peggy Cohen-Kettenis, endocrinologist Henriette Delemarre-van de Waal, and psychiatrist Louis Gooren, soon became the standard therapies for children all across the world who claimed to have gender dysphoria.

Biggs also noted that most psychiatrists have claimed that withholding these treatments from children who think they suffer from gender dysphoria did more damage to them mentally than the physical problems the therapy caused. Refusing to give the treatment, they claimed, was “more harmful to wellbeing in both adolescence and adulthood when compared to cases where physical medical interventions were provided.”

Proponents of these therapies also claimed early on that all the effects could be reversed simply by ending their use. But we now know that claim is false.

Biggs wrote that there are irreversible side effects of these puberty blockers, including the cessation of critical body growth, especially that of genitals. After use of GnRHa on boys, for instance, the penis would cease to grow, and growth would not resume even if the drugs were discontinued.

Additionally, Biggs said that the activists for transsexual alterations and puberty blockers lied to the public about the likelihood that kids supposedly suffering gender dysphoria might just get over their adolescent confusion and change their minds later on. It is likely that a number of children sterilized and transmogrified using the dangerous Dutch protocols would otherwise have turned out to be sexually functional gays or lesbians.

“Clinicians need to explain how they are sure that some of the adolescents being prescribed GnRHa would not have grown into gay or lesbian adults, with their sexuality and fertility intact,” Biggs warned.

Indeed, pop star Demi Lovato is the veritable poster child for this idea that kids just might grow out of their gender confusion. Lovato has declared herself bisexual, then went “non-binary” — and wanted to be called “they/them” — but then changed her mind again and went back to “she/her.” Lovato didn’t employ any of these life-changing therapies or drugs, of course. And with all her changing back and forth, it’s a good thing she didn’t. Just imagine if she had subjected herself to these powerful therapies that have permanent effect!

Biggs next took on the claims from psychiatrists that children who underwent these treatments had a decrease in depression over their gender dysphoria. But Biggs found that a serious look at these claims shows that the studies they were based on are not conclusive. Worse, some of the claims in favor of the emotional stability of protocol users have not been able to be reproduced and so cannot be taken as proof of efficacy.

Indeed, many are waking up to this truth that kids are not safe from depression just because their gender dysphoria fantasies are indulged. One father in Florida sued his daughter’s school for pushing so hard on her so-called gender dysphoria that she tried to commit suicide.

Biggs also found that when the left-wing media touts these fake studies and dubious claims of the transgender lobby, use of the protocols increases commensurate with the media propaganda.

In the end, Biggs finds that there is no proof for the efficacy of these protocols, that use of the drugs might prevent a person from developing “normal” sexual preferences — even if those are homosexual preferences — and result in serious growth deficiencies in children as they age.

Some lawmakers agree. A movement to outlaw gender-affirming care has been growing in the U.S.A.

The American College of Pediatricians even agreed recently that the use of GnRHa has serious drawbacks. The group said the drugs “arrest bone growth, decrease bone accretion, prevent the sex-steroid dependent organization and maturation of the adolescent brain, and inhibit fertility by preventing the development of gonadal tissue and mature gametes for the duration of treatment.”

Still, the American Academy of Pediatrics ignored the deleterious effects of these therapies in order to push a left-wing political agenda, according to whistleblowers.

As The Blaze reported, 6,379 people died between 2013 and June 2019 after taking the hormone blocker Lupron. There were also 41,213 adverse events and 25,645 “serious” reactions reported. Lupron is one of the drugs given to children diagnosed with gender dysphoria.

It seems that the facts are in. The effects of these dangerous drugs are not as safe as they were touted as being, and they do far more damage than good to children who are unfortunate enough to have been subjected to them.

Follow Warner Todd Huston on Facebook at:, or Truth Social @WarnerToddHuston


Warner Todd Huston

Warner Todd Huston has been writing editorials and news since 2001 but started his writing career penning articles about U.S. history back in the early 1990s. Huston has appeared on Fox News, Fox Business Network, CNN, and several local Chicago News programs to discuss the issues of the day. Additionally, he is a regular guest on radio programs from coast to coast. Huston has also been a Breitbart News contributor since 2009. Warner works out of the Chicago area, a place he calls a "target rich environment" for political news.


Join the conversation!

We have no tolerance for comments containing violence, racism, vulgarity, profanity, all caps, or discourteous behavior. Thank you for partnering with us to maintain a courteous and useful public environment where we can engage in reasonable discourse.


Need help, have a question, or a comment? Send us an email and we'll get back to you as soon as possible.


Log in with your credentials

Forgot your details?